Emily is Matt and Caroline’s third child, now with two daughters and one son. From all reports mother and baby are doing well.
Advertisement Facebook Login/Register With: Advertisement Advertisement Firefly’s Nathan Fillion has already been announced.Brown rose to stardom after starring in Stranger Things, opposite Winona Ryder and Matthew Modine. She played psychokinetic teen Eleven, who befriends a gang of misfit kids after escaping a government facility. Twitter LEAVE A REPLY Cancel replyLog in to leave a comment Child actress Millie Bobby Brown, best known for her touching and effectively creepy turn as Eleven in the Netflix hit Stranger Things, is coming to Calgary this April.The 12-year-old actress was announced as a guest of the Calgary Comic and Entertainment Expo this year, which runs from April 27 to 30 at Stampede Park.Also new to the lineup is Christopher Lambert, best known for 1986’s Highlander and 1984’s Greystoke: The Legend of Tarzan and Danielle Panabaker, who plays Killer Frost in Arrow and The Flash.
Deadlines are powerful motivating forces for journalists, tax filers, eurozone negotiators — and bracket pickers. The number of men’s NCAA Tournament brackets submitted per minute by ESPN.com users peaked at 11:51 a.m. EDT on Thursday, mere minutes before the 12:15 p.m tipoff of the first-round opener and the deadline to enter picks, according to data provided by our colleagues at ESPN.com.1Per their request, we’re sharing only the relative magnitude of submissions, not absolute numbers. The maximum rate of bracket submissions per minute on Thursday was more than three times the high of the day before and about five times the max on Monday and Tuesday. All told, even counting the wee hours in the U.S., there were more brackets submitted in just half of Thursday than in all of Tuesday. Not everyone waits until the last minute, though. At ESPN.com, there was an earlier, although lesser, spike in online bracket submissions just after the bracket went up. For every three people who were madly filling in chalk and upsets in their entries just before noon on Thursday, there were two hitting submit on theirs eight minutes after the first Tournament Challenge bracket was submitted at 7:12 p.m. on Sunday.Maybe it’s my bias as a journalist showing, but I think the procrastinators had the right idea: They could benefit from forecasts like ours.Check out FiveThirtyEight’s 2016 March Madness Predictions. At CBSSports.com, the surge came even later. Bracket submissions to the site peaked at 11:59 a.m., according to spokeswoman Annie Rohrs.
As the season winds down for the Ohio State men’s soccer team, the remaining stretch of games might be their toughest test yet.Four out of the next five games will be Big Ten showdowns for the Buckeyes. These games will ultimately decide who wins the conference championship and what team could make it to the NCAA tournament. The Buckeyes’ remaining Big Ten opponents are Penn State, Wisconsin, Michigan and Indiana. The lone non-conference game is against West Virginia. Penn State and Indiana are leading the Big Ten, and Wisconsin and Michigan are tied with OSU for fourth place. OSU is within striking distance of claiming that top spot, making the Buckeyes’ next few games very important.OSU plays Penn State on Sunday in a game that could decide who wins the conference. Penn State sits at 2-0-1 in the conference. They have beaten Michigan State on the road, Michigan at home and tied Northwestern. OSU sits at 1-1 in the Big Ten.“If we want a conference championship we have to beat Penn State,” coach John Bluem said. “If we don’t beat Penn State, I would say we’re probably out of the conference championship race already. So for us it becomes a knockout game already.”Kickoff is at 2 p.m. Sunday at Jesse Owens Memorial Stadium. Bluem said that as the season winds down, OSU cannot lose more games. Every game from this point on means a lot in the conference race and the ability to make the NCAA Tournament.
Play ‘Em Ben Roethlisberger: So much for being rusty. Big Ben returned from his suspension throwing for 257 yards with three touchdowns and one interception against the Browns. This week, he takes on a Dolphins defense that allows 22 points per game and Big Ben’s last game against Miami, 220 yards and three touchdowns. From here on out, Big Ben is a Top Ten quarterback. Matt Cassel: Cassel and the Chiefs offense woke up last week against the Texans, 209 yards with three touchdowns and one interception. Cassel gets another great matchup against Jacksonville, who allows 264 passing yards per game. Look for Cassel to find Dwayne Bowe or Tony Moeaki around the goal line. Consider Cassel as a bye-week filler. Joe Flacco: Flacco has been solid in the past four weeks, throwing six touchdowns versus one interception. Flacco is a must-start this week against Buffalo. Buffalo is known for its horrid defense against the run, but showed holes in the secondary against David Garrard in Week Five, 178 yards with three touchdowns and one interception. Expect Flacco to lean on Ray Rice and Anquan Boldin in the passing attack. Chris Ivory: Ivory took advantage of his rare playing time last week against Tampa Bay, 15 carries for 158 yards. Ivory will continue to get the workload if Pierre Thomas (high-ankle sprain) is out. Ivory will find running lanes against a Browns defense that has allowed 100 yards to opposing running backs in four out of the first six games. If you’re in a bind at the running back position, Ivory is worth picking up. Michael Bush: Darren McFadden is still nursing a hamstring injury, so Bush should see the majority of the carries. The Raiders face a Broncos defense that allows 128 rushing yards per game and Bush has had success against Denver, 133 yards and a touchdown. Before playing Bush, monitor McFadden’s health status. Jeremy Maclin: Maclin ran past the Falcons defense last week, 159 yards and two touchdowns. Maclin will be the focus of the Eagles’ offense because DeSean Jackson will be out with a concussion. Look for continued success as Maclin and Kevin Kolb are developing a tight bond and face a Titans’ pass defense that ranks 27th in the league. Bench ‘Em Chad Henne: Henne has now thrown two touchdowns passes in three straight games after his performance against Green Bay, 239 yards with two touchdowns and one interception. If you’re looking for quarterback help, avoid Henne this week against the Steelers. Henne’s last game against Pittsburgh wasn’t too impressive, 140 yards with one touchdown and one interception. Along with Henne, avoid running backs Ronnie Brown and Ricky Williams. Ryan Torain: Torain looks like the better back in Washington over Clinton Portis, but I’m not jumping on the bandwagon yet. I expect the Bears to bounce back from a poor outing against Seattle, 114 yards and two touchdowns allowed rushing. They will stack the box and force the Redskins to throw the ball. Until Torain puts up consistent numbers, I’ll continue to pass on “The Train.” LeSean McCoy: McCoy is dealing with a rib injury and is questionable for Sunday’s game. Even at full strength, I would advise sitting McCoy. The Titans have a stout run defense that allowed Maurice Jones-Drew 57 yards Monday Night. The Eagles still remain a pass-first offense and will take advantage of the Titans’ weak pass defense. Marques Colston: I am losing patience with the Saints receiver as he continues to be mediocre. He had 53 yards against Tampa Bay. Colston continues to get the majority of the targets, but is not involved in the red zone. It’s tempting to start Colston against Cleveland, but Lance Moore and Robert Meachem continue to be involved in this offense.
BOSTON, MA — The following Wilmington students have been named to Emerson College’s Dean’s List for the Fall 2018 semester:Allison DaniliukSamantha MacDougallThe requirement to make the Dean’s List is a grade point average of 3.7 or higher that semester.About Emerson CollegeLocated in Boston, Massachusetts, opposite the historic Boston Common and in the heart of the city’s Theatre District, Emerson College educates individuals who will solve problems and change the world through engaged leadership in communication and the arts, a mission informed by liberal learning. The College has 3,750 undergraduates and 750 graduate students from across the United States and 50 countries. Supported by state-of-the-art facilities and a renowned faculty, students participate in more than 80 student organizations and performance groups. Emerson is known for its study and internship programs in Los Angeles, Washington, D.C., the Netherlands, London, China, and the Czech Republic. A new, permanent facility on Sunset Boulevard for its L.A.-based program opened in January 2014. The College has an active network of 39,000 alumni who hold leadership positions in communication and the arts. For more information, visit www.emerson.edu.(NOTE: The above announcement is from Emerson College via Merit.)Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email firstname.lastname@example.org.Share this:TwitterFacebookLike this:Like Loading… RelatedSTUDENT SPOTLIGHT: Wilmington’s Allison Daniliuk Named To Dean’s List At Emerson CollegeIn “Education”STUDENT SPOTLIGHT: Wilmington’s Allison Daniliuk Named To Dean’s List At Emerson CollegeIn “Education”STUDENT SPOTLIGHT: 3 Wilmington Students Named To Dean’s List At Regis CollegeIn “Education”
Post a comment 0 Toyota More about 2020 Toyota Corolla Hybrid Toyota Review • 2020 Toyota Corolla Hybrid review: Sip with subtlety Share your voice 2018 Mercedes-Benz E400 Coupe: Drives better than most, and smells better too 2016 Mercedes-Maybach S600 review: Let it semi-autonomously chauffeur your chauffeur More From Roadshow Preview • 2020 Toyota Corolla Hybrid first drive: 53 MPG made simple 2020 Hyundai Palisade review: Posh enough to make Genesis jealous Tags Putting fragrance dispensers in cars is nothing new. But automakers have yet to add a personal twist that also weaponizes the system — that is, until a Toyota patent application surfaced.A recently published patent application from Toyota describes, quite simply, a “vehicle fragrance dispenser system.” As the application notes, this system goes above and beyond the current systems by adding a personal twist. It can use mobile devices to determine if a specific occupant is entering the vehicle, at which point it can dispense one of multiple perfumes specific to the occupant’s tastes. Current systems only have space for one fragrance in the system at a time.Enlarge ImageEven your perfume atomizer will be connected to the cloud in this lovely little dystopia we’re building. USPTO But wait, there’s more. Because some people might have problems with specific fragrances, the system also includes a deodorizer. It can deploy as soon as the occupant leaves the vehicle, returning the car’s scent to neutral as it awaits the next occupant, who might not like the last guy’s preference for fresh pine or whatever. The system can also dispense fragrances ahead of a person entering the car, filling the car with scent instead of forcing the occupant to wait for the HVAC system to do its thing, like current applications.So what about the tear gas? Here’s where it gets clever. Since the system is built to detect the occupants, if it detects an “illegitimate engine start,” as the application says, it can dispense tear gas instead of perfume, likely sending the scofflaw running. Hopefully that deodorizer is capable of removing tear gas from the car, otherwise the actual owner will be in for an eye-opening (and eye-watering) experience later on. Hopefully the trunk has an eye-rinse station.Of course, the beauty of a patent application is that it allows for some wild thinking without necessarily making it to reality. Some automakers routinely apply to patent technologies to beat competitors to the punch. So, while this system might not appear in your next Toyota, it’s good to know that the automaker is thinking about some… unorthodox ways to keep your car safe while also making it smell pretty. 2018 Toyota Century is a Marvel movie star car in waiting 94 Photos Auto Tech Car Industry
1. For anyone looking to upgrade their #NintendoSwitch or get a #NintendoSwitchLite using a trade-in and transfer at a retail store, I just did it. Here’s how my transfer process went and what you should know BEFORE you head in to make the… Switch 😉 pic.twitter.com/RojIgWNHK2— ✨ ashley ✨ (@AshleyEsqueda) August 14, 2019 0 Dan Ackerman/CNET The Nintendo Switch Lite is still more than a month away, but there’s one new piece of Nintendo hardware you can get right now. The so-called V2 version of the dockable Switch has quietly made its way into stores, and some people are even trading in their original hardware for the new model.The difference between the two versions of the modular Switch is a processor upgrade that promises improved battery life (newer processors are often more power efficient than their predecessors). The new V2 battery claim from Nintendo is 4.5 to 9 hours, vs. 2.5 to 6.5 hours for the first-gen hardware. Both V2 and V1 Switches in hand, I ran a battery test on each. For this comparison, I ran non-stop video via the Switch’s YouTube app, with screen brightness at 100% and auto-brightness and sleep timers turned off. Note that V1 Switch used here has some mileage on it, but has been used almost exclusively docked. (What can I say? I’m a docker, not a hander.)Nintendo Switch V2: 4 hours 55 minutesNintendo Switch V1: 3 hours 30 minutes That’s a notable improvement, but is it worth selling or trading in your current Switch for a new one? I’d say it’s doubtful, especially as you’ll have to transfer game saves from one system to another, a process Nintendo complicates by deleting the data from the original Switch as part of the transfer process.My colleague Ashley Esqueda did just that, transferring her saves as part of a trade-in right at a retail store. She describes the process (and it’s a bit of a hassle) in great detail in this excellent Twitter thread. Tags Computers Gaming Share your voice Post a comment I tried something different, transferring the saved content for a single game from the V1 Switch to the V2. By doing this, both Switch units can use the same account, but your saved game files are deleted from the original Switch when they get transferred to the new one. It’s also worth keeping track of which one is your primary Switch, which is an important designation Nintendo keeps track of. On your primary device, other user accounts on the same hardware can access your owned content. On a secondary device, only you can. If you’re convinced the Switch V2 is for you, just don’t go out and accidentally buy some old stock that’s still sitting on a store shelf. The only way I could find to tell the hardware apart is the model number stamped on the back. The original reads “HAC-001,” while V2 is “HAC-001 (-01).” But there’s also an easier way to tell the difference — the V2 Switch comes in a box with a red background on its front panel. But even if you just bought a V1 Switch, there’s hope, as Nintendo will swap out an original Switch purchased after July 17 for a new V2 model if you contact the company. See it at Best BuyDisclosure: CNET may get a share of revenue from the sale of products featured on this page. Nintendo
Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global 2 min read Growing a business sometimes requires thinking outside the box. Putting your office chair in its place is such hard work. You have to push the thing where you want it to go, which involves actually touching it and, well, actually thinking a little.Who has time for that?Nissan knows you don’t and feels your Dilbert-like pain. That’s why the carmaker created a creeping fleet of self-parking office chairs to help we lazy worker schlumps deal. Too bad they’re just a concept for now.Related: Spooked by Self-Driving Cars? Get a Load of Daimler’s Awesome Autonomous Big Rig.The gimmicky “smart chairs,” technically called “Intelligent Parking Chairs,” per an announcement this week from Nissan, slowly slink to and fro (without working stiffs in them) using the nerdy tech wizardry of embedded sensors. The sensors communicate with a network of four cameras positioned throughout the room the 360-degree-turning chairs are in. They “generate a bird’s-eye view to wirelessly transmit the chair’s position and its route to destination.” Fancy.To send the wheeled robo-chairs packing — and neatly under desks, where they darn well should be after meetings and such — users simply clap their hands once. Raw power, right in the palm of your delicate white-collar hand.Related: Meet the $25 Standing Desk Made of Collapsible CardboardPretty neat stuff, we think. Also a little goofy to watch in action. Take a seat in your dumb chair and have a look to see what we mean.The semi-autonomous chairs were inspired by Nissan’s forthcoming “Intelligent Parking Assist,” a vehicle self-parking feature that the Japanese company recently showed off using a mobile app prototype and a LEAF electric car, minus a driver. It’s not clear if these sweet seats will ever be available for purchase, though we wouldn’t mind shelling out a bit to park ourselves in one — and to park one.We reached out to Nissan for more details, but have yet to hear back. In the meantime, we’ll be daydreaming about commanding a pack of ergonomically correct conference room chairs, one bossy clap at a time.Related: Sick of Sitting? Tired of Standing? Take a Load Off With This ‘Leaning’ Desk. Register Now » February 17, 2016
December 5, 2016 Register Now » 2 min read Growing a business sometimes requires thinking outside the box. For most of us, a call to 911 is our first impulse when facing an emergency situation. Today, with the rise of social media and advances in technology, people can turn to a smartphone app or social media page for help during crises.From Apple’s Find My Friends to Facebook’s Safety Check, tech giants are creating ways to help people during emergencies. And Google has taken things one step further with Trusted Contacts.Trusted Contacts allows users to share their location with any of their designated “trusted contacts,” while trusted contacts can request the user’s location as well. A person can accept or decline someone’s request, but if they don’t respond, the app will automatically accept the request and share that individual’s location.Users can share their location at any given time, or indefinitely. The app is different than Find My Friends, letting users share their location for a certain period of time, while perhaps walking home alone or out and about at night. Unless a location is shared indefinitely, the app only shows trusted contacts general information about a user’s whereabouts and if they are online. The app works offline too, so if a user’s phone dies, a trusted contact can find out where their last online location was.Google’s product manager David Tattersall tells Mashable, “It basically means then that as long as you’ve got your phone in your pocket, someone can always find you in case of an emergency. You’re always findable.”The app is only available for Android right now, but will be available on iPhones soon. Free Webinar | Sept. 9: The Entrepreneur’s Playbook for Going Global
Free Webinar | Sept 5: Tips and Tools for Making Progress Toward Important Goals Disclosure: Our goal is to feature products and services that we think you’ll find interesting and useful. If you purchase them, Entrepreneur may get a small share of the revenue from the sale from our commerce partners. For the secret sauce behind 150,000 companies’ customer service success—including 83 percent of Fortune 500 firms—look no further than Salesforce, a customer relationship management (CRM) system that gives businesses detailed overviews of their customers to help them better connect with them.Salesforce is unique in that it’s cloud-based, meaning it lets users track customer activity, organize personalized marketing campaigns, collaborate among teams, and manage communities from anywhere and on any device; it’s a completely streamlined experience. And with a bit of training in Salesforce’s platform, you could be jockeying for a bankable new gig (and an impressive new line on your résumé, at the very least): In one survey, certified Salesforce professionals made $17,250 more annually than their uncertified counterparts. Fasttrack yourself to such professional success with 65 hours of learning through the Salesforce Certification Training Bundle. On sale for a limited time, it includes eight classes that cover the platform’s various ins and outs:Salesforce Einstein Discovery: Introduction to AI and Data Science (a $39.99 value)Over the course of 26 lectures, you’ll get a comprehensive run-down of Salesforce’s capability to perform automated AI and data science tasks, which eliminate a need for coding.Salesforce Service Cloud Consultant Certification Course (a $199.99 value)By the time you complete this 115-lesson class on designing and deploying customer service solutions using Salesforce’s Service Cloud and OmniChannel features, you’ll be more than ready to get certified as a Salesforce Service Cloud Consultant.Salesforce Sales Cloud Consultant Certification Course (a $199.99 value)Ace the Sales Cloud Consultant certification exam with this 11-hour course covering different aspects of Salesforce’s performance management tool, including Salesforce Lightning page configuration and creating opportunity record types.Introduction to Salesforce Certification and Career Planning (a $20 value)Explore the various certifications and career opportunities made available by a Salesforce education with this 17-lecture course that includes résumé tips and resources. Complete Salesforce & Salesforce1 New User Training Course (a $40 value)If you aspire to lead a company’s Salesforce initiative one day, this class will get you properly up to speed on what it takes to manage accounts, market to new demographics, utilize the Salesforce1 mobile app, and other relevant skills across 59 lectures.Salesforce Lightning Experience User Training (a $20 value)Dive head-first into brand new Salesforce Lightning Experience interface with the help of this three-hour class featuring insights on its new reports and dashboards. The Complete Salesforce Administrator Certification Course (a $195 value)A study guide for the Salesforce Administrator Certification Exam and hands-on experience with Salesforce’s interface are both included in this 77-lesson course.Salesforce Platform App Builder Developer 401 Certification (a $195 value)This 20-hour course is modeled after the official study guide for the Salesforce Platform App Builder Certification exam. Translation: It covers just about everything you need to know to pass said exam, from workflow automation procedures to setting up security permissions.You’d be out $909.97 if you bought each of those courses separately, but with the Salesforce Certification Training Bundle, lifetime access to all of that training is available for just $29.99. 3 min read Register Now » Attend this free webinar and learn how you can maximize efficiency while getting the most critical things done right. December 18, 2018
Categories: News,Webber News Proposals address current technology, allow consumer choiceTwo separate plans authored by state Rep. Michael Webber, of Rochester Hills, making vehicle platooning easier for semi-trucks, and purchasing insurance bundles easier for consumers in Michigan were recently signed into law.House Bill 5749 exempts semi-trucks operating in a platoon from a requirement that they keep a certain distance from each other. Vehicle platooning refers to cars or trucks that are electronically linked to coordinate speeds in order to enhance safety, save time and energy, and reduce emissions. It is already legal on Michigan roads.“Michigan is a powerhouse of technology for autonomous vehicles throughout the country,” said Webber, of Rochester Hills. “Vehicle platooning increases the safety of self-driving vehicles on Michigan roads and enhances the transportation of goods and services.”House Bill 6432 allows health insurers to bundle multiple types of insurance, such as life insurance or auto insurance, and sell it as a single package for the convenience of consumers. Webber’s measure strikes a 1986 law, which prohibited health insurance agents from selling any type of insurance other than health insurance.“Rather than fulfilling their insurance needs through multiple sellers, Michigan families would rather purchase an insurance bundle through an insurer they already know and trust,” Webber, who serves on the House Insurance Committee. “Michiganders will now have an easier time bundling together crucial insurance services that protect them and their families.”House Bills 5749 and 6432 are now Public Acts 377 and 430 of 2018.### 20Dec Pair of Rep. Webber plans recently signed into law by governor
March 18, 2016 –shares 2019 Entrepreneur 360 List 3 min read Income Inequality The only list that measures privately-held company performance across multiple dimensions—not just revenue. Reuters Amazon Resisting Efforts to Reveal Gender Pay Differences Amazon.com Inc. should allow shareholders to vote on a proposal on gender pay equality, the U.S. securities regulator decided this week in rejecting the retailer’s request to omit the measure from its annual ballot.Arjuna Capital, the activist arm of investment firm Baldwin Brothers Inc., said it submitted the proposal to Amazon and eight other technology companies, including eBay Inc. and Intel Corp.Only Amazon sought permission from the Securities and Exchange Commission to omit the proposal, Arjuna said.Arjuna called for an October deadline for Amazon to report the difference between males’ and females’ pay and its plans to close the gap, according to a filing on the SEC’s website.While such proposals generally face long odds, just getting one on the ballot of a high-profile company like Amazon can be a catalyst for change.In a ruling on Tuesday, the SEC said it did not agree with Amazon that the proposal was “so inherently vague or indefinite” that it would impede implementation.Amazon, which estimates that as of July women made up 39 percent of its global workforce and 24 percent of managers, did not immediately respond to a request for comment on whether it would include the proposal on its ballot.”We’re committed to fairly and equitably compensating all our employees, and we review all employee compensation on at least an annual basis to ensure that it meets that bar,” Amazon said in an emailed statement.Amazon added that it was already working with organizations such as Code.org, the Anita Borg Institute and Girls Who Code to increase women’s and minorities’ involvement in the technology industry.The SEC ruling comes as technology companies face scrutiny over diversity and compensation equity issues.”It’s not simply a social justice issue,” said Natasha Lamb, director of shareholder engagement at Arjuna. “It’s an issue that affects performance, affects the company’s ability to attract and retain top talent.”Lamb said Arjuna withdrew proposals at Apple Inc and Intel after they took action on the issue. Intel, for example, earmarked $300 million for diversity and said it found its male and female employees were equally paid.EBay shareholders rejected Arjuna’s first proposal on gender pay equity last year after the board opposed it. Arjuna said it resubmitted the proposal at eBay this year and expanded its effort to a total of nine companies.EBay declined to comment.(Editing by Stephen R. Trousdale and Lisa Von Ahn) Add to Queue Image credit: Shutterstock Next Article This story originally appeared on Reuters Apply Now »
July 15, 2016 Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful. Sometimes you wish that cell towers would just stop working for a while…As Pokémon Go fever captures the hearts, minds and data plans of the nation, the following tweet was sent out from the Arlington National Cemetery’s official account:We do not consider playing “Pokemon Go” to be appropriate decorum on the grounds of ANC. We ask all visitors to refrain from such activity.— Arlington Cemetery (@ArlingtonNatl) July 12, 2016Just to recap, Arlington National Cemetery is where 400,000 veterans, including over 300 Medal of Honor recipients, have been laid to rest after serving our country. It is the place where the Tomb of the Unknown Soldier stands, dedicated to service members who died without having their remains identified, and is the site of The Eternal Flame, which marks the grave of assassinated President John F. Kennedy. So knowing all of that, if Arlington National Cemetery still seems like a suitable place to play a child’s game on your phone, might we suggest you also run off and play it in an area with more cliffs?Related: The 5 Most Ridiculous Pokémon Go Stories of the Week –shares Next Article Add to Queue Entrepreneur Staff Entrepreneur Staff 1 min read Image credit: John Greim | Getty Images Hey Idiots, Arlington National Cemetery Wants You to Stop Playing Pokémon Go on the Tombs of Fallen Veterans Fireside Chat | July 25: Three Surprising Ways to Build Your Brand Pokémon Enroll Now for $5
New TDWI Research Report Explores the Challenges and Benefits of Cloud Data Management PRNewswireJune 11, 2019, 1:47 pmJune 11, 2019 Report Helps Enterprises Navigate the Complexity of Cloud and Hybrid Data Environments to Maximize the Success of Their Cloud Data Management EffortsTDWI Research has released its newest Best Practices Report, Cloud Data Management: Integrating and Processing Data in Modern Cloud and Hybrid Environments. This original, survey-based report looks at the many dimensions of cloud data management (CDM) so data professionals and their business counterparts can understand the benefits of CDM and how they can organize a successful program.The author of the report, Philip Russom, Ph.D., is senior director of TDWI Research for data management. He explains that technical users are lured to the cloud because of its speed, scale, elasticity, and low level of maintenance; business people are drawn to its agility, low cost, and ability to support new data-driven business practices. Cloud data management is about managing old and new data in hybrid data architectures that span on-premises and cloud systems so enterprises have data they can trust, govern, and leverage for business value with the latest in business analytics and data-driven operational innovations.Marketing Technology News: Vidyard Expands Offering to Bring Personalized Video App to Any Sales Professional, No Matter How They WorkCDM involves working with database management systems, data integration tools, related platforms, and the numerous best practices users perform with them. Modernizing this complex environment — especially consolidating traditional enterprise data and modern big data using on-premises and cloud-based tools and platforms — is challenging in part because clouds are making data more heavily distributed than it has ever been. For example, the report identifies key barriers to successful CDM, including issues in governance, data migration, data quality, and tool maturity.Marketing Technology News: AdQuick.com Releases Campaign Genius, so Marketers can Plan and Optimize Out of Home (OOH) Advertising Campaigns in MinutesThe report examines the many dimensions of CDM (which is also known as cloud data warehousing, data-as-a-service, and hybrid data management), explores who owns and maintains CDM projects, and looks at how enterprises are currently addressing CDM issues.Marketing Technology News: Agency Veteran Joao Machado Joins as Sabio’s SVP of Product Marketing Cloud and Hybrid Environmentscloud data managementData ManagementMarketing TechnologyNewsTDWI Research Previous ArticleBidtellect’s Answer for Growing Advertiser Demand is Major Infrastructure Environment OverhaulNext ArticleSelligent Marketing Cloud to Showcase Collaboration with Genesys at Xperience19
Source:http://www.frontiersin.org/ Reviewed by Alina Shrourou, B.Sc. (Editor)Jan 11 2019In a trial of one of the main class of prescription sleeping pills, half the participants slept through a fire alarm as loud as someone vacuuming next to their bed. But a newer alternative preserves the ability to wake in response to danger signals, according to a new research.Published this week in Frontiers in Behavioral Neuroscience, the study showed that mice given the experimental hypnotic drug DORA-22 wake as quickly when threatened as drug-free sleepers – and then fall back asleep as quickly as ones given standard sleeping pills, once the threat is gone.Common sleeping pills muffle your sleeping brain’s ‘intruder alert’Even during sleep the brain continuously processes sensory information, waking us if it detects a threat. But the most widely prescribed class of sleeping pills, known as benzodiazepines, makes us less likely to rouse in response to sensory input.”Benzodiazepines stimulate the widespread brain receptor GABA-A, which makes us sleepy but also suppresses off-target brain areas – including the ‘gatekeeper’ that decides which sensory inputs to process,” explains study senior author Professor Tomoyuki Kuwaki of Kagoshima University, Japan.Over the last decade, researchers have been developing a new class of hypnotic drugs called dual orexin receptor antagonists (DORAs). DORAs more selectively target the brain’s sleep/wake pathways, which gives them safety advantages over benzodiazepines. These include a reduced ‘hangover effect’, with DORAs less likely to affect driving ability the day after use.Kuwaki and colleagues hypothesized that the selectivity of DORAs could make them a safer alternative during sleep as well – by allowing the brain’s sensory gatekeeper to stay vigilant to threats.DORA-22 allows mice to wake to a threat, but still helps them sleepThe group tested their theory in mice.The mice were dosed and tested after dark, when they are normally most active. One group was administered DORA-22, another a benzodiazepine called triazolam – and a third group was given placebo as a control.”DORA-22 and triazolam had similar sleep promoting effects, extending the duration of deep sleep by 30-40% compared to placebo,” reports Kuwaki.Related StoriesSleep disorders in patients with low back pain linked to increased healthcare visits, costsSleep makes synapses ready for new learningSleep quality could be indicator for later Alzheimer’s disease finds studyOne to four hours after dosing, the deep-sleeping mice were presented with a threatening stimulus: the smell of a fox, a high-pitched noise like a dog whistle, or trembling of their cage. The trembling frequency was designed to match that of an earthquake – a serious threat in Kuwaki’s native Japan and many other parts of the word.”As expected, arousal in response to these threatening stimuli was delayed significantly in the triazolam treatment, but not in the DORA-22 treatment, compared to placebo.Even more promising, the sleep-promoting effect of DORA-22 remained after the rude awakening.”Even though the DORA-22-treated mice were quickly woken by a threat, they subsequently fell back asleep as quickly as with triazolam, and significantly faster than with placebo.”To help demonstrate that the delay in waking to a threat during triazolam treatment was due specifically to inhibition of sensory gating in the brain, the researchers also tested the sleeping mice with a non-sensory stimulus.”The three groups woke equally quickly when we suddenly reduced the amount of oxygen in their cage. This suggests that the delay in rousing to threatening stimuli caused by triazolam was not caused by a general inhibition of waking systems in the brain.”Human studies are needed to confirm DORA safety and efficacy”Although it remains to be seen whether DORAs have the same properties when used in humans, our study provides important and promising insight into the safety of these hypnotics.”Since 2014, another DORA called surovexant has gained regulatory approval in Japan, the USA and Australia. So far, the high cost and limited clinical testing of surovexant have limited its use, amid concerns that doses high enough to significantly improve sleep lead to drowsiness the following day. New DORAs currently in development could overcome this hangover effect if they are cleared more quickly from the body than suvorexant, so that their effects are less likely to last beyond bedtime. Keep your eyes peeled.
Reviewed by James Ives, M.Psych. (Editor)Apr 29 2019Mesothelioma patients are twice as likely to survive for two years or longer, if they are treated with a high dose of radiation to the affected side of the trunk, according to research presented at the ESTRO 38 conference.Mesothelioma is a rare but aggressive form of cancer that grows in the layers of tissues surrounding the lungs. It is usually caused by exposure to asbestos. Patients typically only live for a year or two following diagnosis and treatment options are very limited.The study looked at patients whose cancers could not be completely removed with surgery and the researchers say their findings have the potential to change treatment and outcomes for this group of patients.The study was led by Dr Marco Trovo MD, chief of the Radiation Oncology Department at University Hospital of Udine, Italy. He said: “There is an urgent need for more effective treatments for mesothelioma. Surgery can be given to these patients, but it is often impossible to remove all of the tumors.”Patients with mesothelioma are sometimes given radiotherapy to help control their symptoms. However, radiotherapy has evolved dramatically in the last few years so we wanted to see if it could now be used to prevent the cancer from spreading to nearby tissue, hopefully bringing improvements in survival.The study involved 108 patients with malignant pleural mesothelioma who were treated at the National Cancer Institute of Aviano, Italy, between 2014 and 2018. All were given surgery to remove some tumor tissue, followed by chemotherapy.Half were randomly assigned to receive radical hemi-thoracic radiotherapy, meaning the radiation was delivered to either the left or right side of their trunk, depending on where the tumor was located. This involved 25 treatments delivering a total dose of 50 Gy to the left or right side of the trunk, as well as an extra 60 Gy dose to the precise location of the tumor. The other patients received a more typical palliative form of radiotherapy. This involved five to ten treatments delivering a total dose of 20-30 Gy to the precise location of the tumor.Related StoriesAdult survivors of pediatric brain tumors may experience cognitive, socioeconomic burdensNew research uncovers mechanism behind the newest generation of cancer drugsRemoving asbestos from schools likely to increase cases of mesotheliomaOf the patients who received the aggressive radiotherapy treatment, 58% were still alive two years later. In the patients who received the palliative radiotherapy, 28% were still alive two years later.Around 20% of patients receiving radical hemi-thoracic radiotherapy suffered radiation pneumonitis (inflammation of the lung). Other sides effects included weakness, nausea and mild inflammation of the oesophagus.Dr Trovo said: “This research shows a clear survival benefit in using this type of radiotherapy for mesothelioma patients whose tumors can only partially be removed by surgery. We believe that this should be considered the new standard of care for these patients.”He hopes that even greater gains in survival could be made by treating patients with radiotherapy followed by targeted immunotherapy (where the body’s own immune system is encouraged to fight cancer cells).Professor Umberto Ricardi, President of ESTRO and head of the Department of Oncology at the University of Turin, Italy, who was not involved in the research, said: “This is an extremely positive result that brings good news to patients with this rare and difficult-to-treat cancer. To ensure these patients benefit from this type of treatment, it’s important that they are referred to a specialist cancer center with the right expertise and equipment to carefully plan and deliver the most effective radiotherapy treatment, and manage any side effects that occur.” Source:https://www.estro.org/
The citizenship bill does not require any changes if Clause 6 of the Assam Accord is implemented properly, says Assam Chief Minister Sarbananda Sonowal about the proposed legislation which the top BJP leadership has vowed to bring back if voted back to power.In an interview to PTI, the student leader-turned politician said that the bill will be brought after arriving at a consensus with all stakeholders.“It (amending the Act) is not a new thing as amendments were taken up nine times before this also. This is a continuous process since 1950,” he said, adding the BJP will ensure constitutional safeguards to Northeast’s political, cultural, social and linguistic identity.Implementing the Assam AccordWhen asked if the Assam government will request the Centre to make necessary changes in the existing bill to allay apprehensions of the people here, Sonowal said that is not needed if the Clause 6 of the Assam Accord is implemented properly.The Clause 6 of the Assam Accord, which was signed in 1985 after the Assam Agitation of 1979-85, envisages that appropriate constitutional, legislative and administrative safeguards, should be provided to protect, preserve and promote the cultural, social, linguistic identity and heritage of the people of Assam.“If Clause 6 is implemented in letter and spirit, then the indigenous people of Assam are well guarded and protected. That was the agenda ought to be taken up on priority by earlier governments, but it was never seriously considered, Sonowal said.“Now the Prime Minister has taken up the matter with sincerity, commitment and dedication. So, I believe once it is implemented, we have nothing to worry. If Clause 6 is implemented, we have no issue with the citizenship bill, even if it comes in the current form,” he added.Several groups and parties have opposed the bill, which was passed by the Lok Sabha on January 8 but was not tabled in Rajya Sabha and seeks to provide Indian citizenship to Hindus, Jains, Christians, Sikhs, Buddhists and Parsis from Bangladesh, Pakistan and Afghanistan after six years of residence in India even if they do not possess any document.Interestingly, though the BJP top brass has been talking about the citizenship bill in poll rallies, the state leaders have not raised the issue in their meetings and speeches. State minister Himanta Biswa Sarma had earlier said that the citizenship bill was a non-issue in the state and the people are more concerned about national issues.Addressing issuesSonowal was once president of the influential All Assam Students’ Union (AASU), which has been at the forefront of the protests against the citizenship bill across the Northeast in the past several months.When told out that the concerns raised by people of Assam and the Northeast were not taken into account while drafting the bill, he disagreed and said the Clause 6 has been taken at the highest level for the first time in the history.“It is Modi-ji who has taken it up and ultimately constituted a high-level committee by the Union Cabinet comprising only Assamese people from different fields. It was given very clear terms of references. The committee has been asked to prepare a report on how Constitutional safeguards can be ensured in best possible manner,” he added.Also read: Protests against Citizenship Bill rock Assam The existence of the nine-member committee is in a lurch with its fifth member and chairman MP Bezbaruah withdrawing from it in January. The other four members refused to be a part of it in protest of the Citizenship Bill, are a representative of the AASU, eminent littérateurs Nagen Saikia and Rong Bong Terang along with educationalist Mukunda Rajbongshi.On resignation of the eminent personalities from the high-level committee, the Chief Minister said, “It is because of chaos and unnecessary false propaganda by Congress, Leftists and some section intellectuals and media.” On the mahagathbandhanSonowal also took a dig at the proposed mahagathbandhan of opposition parties saying the ambitious grouping is dreaming of dethroning Prime Minister Narendra Modi but will “collapse soon” as it does not have any policy on patriotism, integration and service to the nation. He claimed the constituents of this ‘grand alliance’ are together during the ongoing Lok Sabha elections only for their vested interests.“They do not have any policy of integration, service to nation and patriotism. The mahagathbandhan is mainly just to get power. They are all with vested interest,” he said. The members usually stay different, but sometimes they come on the same platform but with different self interests, he added. “So, there is no national interest in it. I have not seen any national interest within themselves. That is why, I firmly believe that it will collapse soon,” he asserted.Also read: Amit Shah focusses on NRC, Citizenship Bill at WB rallyAsked about the BJP’s prospects in Assam in this Lok Sabha elections, Sonowal claimed the saffron party along with its allies AGP and BPF will bag at least 12 seats out of 14 in the state. In 2014, the BJP won seven out of 14 Lok Sabha seats in Assam, the Congress and the AIUDF had three MPs each and one member was an Independent. The two BJP allies, BPF and AGP, had no representation in the Lower House of Parliament. Sonowal strongly refuted allegation of Modi failing to fulfil the promises made in 2014 elections, especially on deporting the illegal infiltrators from Assam, and claimed that update work of the National Register of Citizens (NRC) and steps to implement the Assam Accord are being done to accomplish the task. COMMENTS Amid protests, Lok Sabha passes Citizenship Bill SHARE SHARE SHARE EMAIL Opposition parties protest as Govt moves Constitution amendment bill RELATED NE ‘bandh’ begins against Citizenship Amendment Bill Published on Citizenship (Amendment) Bill COMMENT Assam Sarbananda Sonowal, Chief Minister of Assam (File photo) April 21, 2019